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> Major New Paper On Haplogroup E1b1 (e-p2)
kosmonomad
сообщение 18.1.2011, 20:49
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http://dienekes.blogspot.com/2011/01/major...-e1b1-e-p2.html

http://www.plosone.org/article/info:doi/10...al.pone.0016073

Цитата
They sequenced ~45kb in 13 E1b1 chromosomes, producing an updated phylogeny of the -haplogroup (left).

As you can see, increased phylogenetic inference comes at the cost of increasingly long-winded haplogroup designations; hopefully I'll manage to familiarize myself with the new terminology soon enough, and update this post with my comments.

UPDATE:

From the paper:

Haplogroup E1b1 now contains two basal branches, E-V38 (E1b1a) and E-M215 (E1b1b), with V38/V100 joining the two previously separated lineages E-M2 (former E1b1a) and E-M329 (former E1b1c). Each of these two lineages has a peculiar geographic distribution. E-M2 is the most common haplogroup in sub-Saharan Africa, with frequency peaks in western (about 80%) and central Africa (about 60%). The same haplogroup is also present in North Africa, although at a lower frequency (usually below 10%) [9]–[11]. Haplogroup E-M329, on the other hand, was observed almost exclusively in eastern Africa [10], [12 and R.S. unpublished data], where E-M2 is virtually absent. The second basal branch of E1b1, E-M215, has a broad geographic distribution from southern Europe to northern and eastern Africa where it has been proposed to have originated [8]. The new topology here reported has important implications as to the origins of the haplogroup E1b1. Using the principle of the phylogeographic parsimony, the resolution of the E1b1b trifurcation in favor of a common ancestor of E-M2 and E-M329 strongly supports the hypothesis that haplogroup E1b1 originated in eastern Africa, as previously suggested [10], and that chromosomes E-M2, so frequently observed in sub-Saharan Africa, trace their descent to a common ancestor present in eastern Africa.

and:

Within E-M35, there are striking parallels between two haplogroups, E-V68 and E-V257. Both contain a lineage which has been frequently observed in Africa (E-M78 and E-M81, respectively) [6], [8], [10], [13]–[16] and a group of undifferentiated chromosomes that are mostly found in southern Europe (Table S2). An expansion of E-M35 carriers, possibly from the Middle East as proposed by other Authors [14], and split into two branches separated by the geographic barrier of the Mediterranean Sea, would explain this geographic pattern. However, the absence of E-V68* and E-V257* in the Middle East (Table S2) makes a maritime spread between northern Africa and southern Europe a more plausible hypothesis.


PLoS ONE 6(1): e16073. doi:10.1371/journal.pone.0016073

A New Topology of the Human Y Chromosome Haplogroup E1b1 (E-P2) Revealed through the Use of Newly Characterized Binary Polymorphisms


Beniamino Trombetta et al.

Haplogroup E1b1, defined by the marker P2, is the most represented human Y chromosome haplogroup in Africa. A phylogenetic tree showing the internal structure of this haplogroup was published in 2008. A high degree of internal diversity characterizes this haplogroup, as well as the presence of a set of chromosomes undefined on the basis of a derived character. Here we make an effort to update the phylogeny of this highly diverse haplogroup by including seven mutations which have been newly discovered by direct resequencing. We also try to incorporate five previously-described markers which were not, however, reported in the 2008 tree. Additionally, during the process of mapping, we found that two previously reported SNPs required a new position on the tree. There are three key changes compared to the 2008 phylogeny. Firstly, haplogroup E-M2 (former E1b1a) and haplogroup E-M329 (former E1b1c) are now united by the mutations V38 and V100, reducing the number of E1b1 basal branches to two. The new topology of the tree has important implications concerning the origin of haplogroup E1b1. Secondly, within E1b1b1 (E-M35), two haplogroups (E-V68 and E-V257) show similar phylogenetic and geographic structure, pointing to a genetic bridge between southern European and northern African Y chromosomes. Thirdly, most of the E1b1b1* (E-M35*) paragroup chromosomes are now marked by defining mutations, thus increasing the discriminative power of the haplogroup for use in human evolution and forensics.




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Y-DNA: R1a>Z283>Z280>CTS1211>YP1019>YP1033+ BY27605+ Central-Eurasian-2, R1a1a1b1a2b
mt-DNA: H
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Sergey Lutak
сообщение 2.2.2011, 22:36
Сообщение #2


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Да, классификация нашей гаплогруппы E1b1b1 (M35) подверглась очередной ревизии. smile.gif
Cruciani выделил в ней много новых СНиПов и подгрупп.
В частности, название моей гаплогруппы E1b1b1a2 (V13) по новой классификации, вероятно, будет E1b1b1a1b, т.е. удлинится на один знак. Это потому, что между M35 и M78 найден новый СНиП V68.


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aka Moesus

Y-ДНК: E1b1b1a1b*-V13
мито-ДНК: H1b*-16356C
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